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What are the MTHFR Genetic Defects

Dosing information Usual Adult Dose for Pernicious Anemia: Initial dose: 100 mcg intramuscularly or deep subcutaneous once a day for 6 to 7 days If clinical improvement and reticulocyte response is seen from the above dosing: 100 mcg every other day for 7 doses, then: 100 mcg every 3 to 4 days for 2 to 3 weeks, then: Maintenance dose: 100 to 1000 mcg monthly Duration of therapy: Life Comments: Administer concomitant folic acid if needed

Mandal, Raju K., et al

Choosing the right form and dose depends on your symptoms, delivery preference, and whether you're dealing with local inflammation or systemic dysfunction

10.1111/j.1749-6632.2010.05627.x Ann